according to the measurement net recently, according to the international famous journals "facedchangederiinmenhierarchstion" report, institute of chemistry, Chinese academy of sciences, key laboratory of photochemical court with high specific surface area of one-dimensional nanomaterials and the preparation of a more sensitive electrochemical luminescence nano biosensors. The study also is low (material preparation of biosensor provides an important theoretical and experimental basis.
From bacteria to humans and all living things in using & other; Biological molecular switch & throughout; To monitor the environment. Such & other; Switch & throughout; , that is, is made from polymer or protein, can change the shape of the molecule. These and other Molecular switch & throughout; Attractive is that they were small enough to inside cells & other; Office & throughout; And very targeted, enough to handle very complex environments. These natural & other; Switch & throughout; Inspired, nano biosensors arises at the historic moment.
According to relevant personnel of Chinese academy of sciences, biological sensors is using immobilized biological components, such as enzymes, antigen, antibody, hormone, or cells of the organism itself, organelles, such as organization as the sensing element made of sensors. According to the different molecular recognition element that biological sensors can be divided into the enzyme sensor, microbial sensors, sensor, organelles sensors, sensor, etc.; According to the signal conversion components can be divided into different electrochemical biosensors, semiconductor biosensor, calorimetric biosensors, metering type biosensor, sound type biosensor, etc., among them, the electrochemical biosensors because of its small volume, high resolution, short response time, you need less samples, small damage to living cells, etc, are widely used in the pharmaceutical industry, food testing and environmental protection and other fields.
Today, nanotechnology intervention is provides new vitality to the development of electrochemical biosensors. Nanometer material has small size effect, surface effect, quantum size effect and macroscopic quantum tunneling effect, etc., make it show the peculiar chemical and physical properties. Nanometer materials applied in the field of electrochemical biosensors, not only improves the detection performance of the sensor, and improve the chemical and physical properties of the sensor and its detection sensitivity of biological molecules, or cells, also is able to shorten the testing time, at the same time also realized the high throughput analysis of real-time detection.
With the development of nanotechnology and biosensors have merged, more and more new nano biosensors, such as quantum dots, polymer, nucleoside ligands such as nano biosensors. Future nano Watson sensor biosensor development direction should be integrated multi-functional detection machines, portable, one-off fast, it can be widely used in food, environment, battlefield, rapid detection in the field of human diseases. For example, pathogens or pesticide residues in food and beverage ingredients rapid sensitive detection; Environment pollution gases or metal ions pollution in remote monitoring and control; Human blood components and rapid real-time detection of pathogens, battlefield and rapid detection of chemical and biological weapons and explosives. But at the same time, a new generation of nanotechnology biosensor also faces many challenges, such as higher sensitivity, specificity, biocompatibility, a variety of technology integration, simplified test method, preparation technology, mass production, cost effectiveness, etc. To this, the biosensor research and development team, experts say, molecular self-assembly process simple and controllable, can achieve rapid replication, and lower cost, the biosensor has a very important role in promoting the development of, is advantageous to the high sensitivity, low cost, disposable biosensor development. And biological molecular self-assembly technique deserves more attention, it has natural biological compatibility, excellent performance, or will become another new field in the development of biosensors.
